Brief Information of the Compound and Protein
Compound Name
1-[(2S)-3-(4-cyanophenyl)-1-(3,4-dihydro-1H-isoquinolin-2-yl)-1-oxopropan-2-yl]-3-(4-fluorophenyl)urea
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PubChem ID
CID: 168286767
Canonical SMILES
Fc1ccc(NC(=O)N[C@@H](Cc2ccc(cc2)C#N)C(=O)N2CCc3ccccc3C2)cc1
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Compound Formula C26H23FN4O2
Compound Structure
Protein Name
N-formyl peptide receptor 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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N-formyl methionyl peptide receptor
Uniprot ID
P25090
Gene Name
FPR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000018 HL-60 Homo sapiens (Human)  2
1
EC50 = 240 nM
   TI
   LI
   LO
   TS
2
IC50 = 30 nM
   TI
   LI
   LO
   TS