Brief Information of the Compound and Protein
Compound Name
1-[(2S)-3-(4-cyanophenyl)-1-(4,4-difluoropiperidin-1-yl)-1-oxopropan-2-yl]-3-(4-fluorophenyl)urea
    Show/Hide
PubChem ID
CID: 168293205
Canonical SMILES
Fc1ccc(NC(=O)N[C@@H](Cc2ccc(cc2)C#N)C(=O)N2CCC(F)(F)CC2)cc1
    Show/Hide
Compound Formula C22H21F3N4O2
Compound Structure
Protein Name
N-formyl peptide receptor 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
N-formyl methionyl peptide receptor
Uniprot ID
P25090
Gene Name
FPR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000018 HL-60 Homo sapiens (Human)  2
1
EC50 = 19500 nM
   TI
   LI
   LO
   TS
2
IC50 = 30100 nM
   TI
   LI
   LO
   TS