Brief Information of the Compound and Protein
Compound Name
1-[(2S)-3-(4-cyanophenyl)-1-(7-fluoro-4,4-dimethyl-1,3-dihydroisoquinolin-2-yl)-1-oxopropan-2-yl]-3-(4-fluorophenyl)urea
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PubChem ID
CID: 168284664
Canonical SMILES
CC1(C)CN(Cc2cc(F)ccc12)C(=O)[C@H](Cc1ccc(cc1)C#N)NC(=O)Nc1ccc(F)cc1
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Compound Formula C28H26F2N4O2
Compound Structure
Protein Name
N-formyl peptide receptor 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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N-formyl methionyl peptide receptor
Uniprot ID
P25090
Gene Name
FPR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000018 HL-60 Homo sapiens (Human)  2
1
EC50 = 1600 nM
   TI
   LI
   LO
   TS
2
IC50 = 600 nM
   TI
   LI
   LO
   TS