Brief Information of the Compound and Protein
Compound Name
5-cyclopropyl-2-[cyclopropylmethyl-[(1R)-1-[4-[5-methyl-2-(5-oxo-4H-1,2,4-thiadiazol-3-yl)phenyl]phenyl]ethyl]amino]-N-cyclopropylsulfonyl-1,3-thiazole-4-carboxamide
    Show/Hide
PubChem ID
CID: 168275711
Canonical SMILES
C[C@@H](N(CC1CC1)c1nc(C(=O)NS(=O)(=O)C2CC2)c(s1)C1CC1)c1ccc(cc1)-c1cc(C)ccc1-c1nc(=O)s[nH]1
    Show/Hide
Compound Formula C31H33N5O4S3
Compound Structure
Protein Name
Chemerin-like receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor-like
>
Chemerin receptor
Uniprot ID
Q99788
Gene Name
CMKLR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000681 CAL-1 [Human melanoma] Homo sapiens (Human)  1
1
EC50 = 190 nM
   TI
   LI
   LO
   TS