Brief Information of the Compound and Protein
Compound Name |
cis-2,6-Dimethyl-4-(6-(5-(1-methylcyclopropoxy)-1H-indazol-3-yl)pyrimidin-4-yl)morpholine
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PubChem ID | |||||
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Compound Structure |
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Protein Name |
Leucine-rich repeat serine/threonine-protein kinase 2
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Protein Classification |
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase LRRK family
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Uniprot ID | Gene Name | LRRK2 |
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Biochemical Assays
1 | EC50 ~ 1.22 nM | ||
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2 | IC50 = 0.4 nM | ||
3 | IC50 = 0.5 nM | ||
4 | IC50 = 0.76 nM | ||
5 | IC50 = 1 nM | ||
6 | IC50 ~ 1.8 nM | ||
7 | IC50 ~ 3.5 nM | ||
8 | IC50 ~ 6.3 nM |