Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[(1S)-1-[(3-pyridin-4-yl-1H-indazol-5-yl)amino]ethyl]benzonitrile
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 PubChem ID
CID: 168297874
Canonical SMILES
C[C@H](Nc1ccc2[nH]nc(-c3ccncc3)c2c1)c1cccc(c1)C#N
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Compound Formula C21H17N5
Compound Structure
Protein Name
 Protein Info 
Leucine-rich repeat serine/threonine-protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase LRRK family
Uniprot ID
Q5S007
Gene Name
LRRK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 40000 nM
   TI
   LI
   LO
   TS
2
EC50 = 50000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 23 nM
2 IC50 = 67 nM