Brief Information of the Compound and Protein
Compound Name
N-[3-[5-(2-aminopyrimidin-4-yl)-2-(1-cyclopropylpiperidin-4-yl)-1,3-thiazol-4-yl]-2-fluorophenyl]-2,5-difluorobenzenesulfonamide
    Show/Hide
PubChem ID
CID: 156441712
Canonical SMILES
Nc1nccc(n1)-c1sc(nc1-c1cccc(NS(=O)(=O)c2cc(F)ccc2F)c1F)C1CCN(CC1)C1CC1
    Show/Hide
Compound Formula C27H25F3N6O2S2
Compound Structure
Protein Name
Nuclear receptor subfamily 1 group I member 2
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group I
>
Nuclear hormone receptor subfamily 1 group I member 2
Uniprot ID
O75469
Gene Name
NR1I2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
EC50 = 6210 nM
   TI
   LI
   LO
   TS