Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[4-methyl-3-[[2-[3-[(1-prop-2-enoylpiperidin-4-yl)amino]anilino]pyrimidin-5-yl]carbamoyl]phenyl]isoquinoline-6-carboxamide
    Show/Hide
 PubChem ID
CID: 168292604
Canonical SMILES
Cc1ccc(NC(=O)c2ccc3cnccc3c2)cc1C(=O)Nc1cnc(Nc2cccc(NC3CCN(CC3)C(=O)C=C)c2)nc1
    Show/Hide
Compound Formula C36H34N8O3
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase BTK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Tec family
Uniprot ID
Q06187
Gene Name
BTK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 58 nM
   TI
   LI
   LO
   TS