Brief Information of the Compound and Protein
Compound Name
US10294246, Compound No. 92
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PubChem ID
CID: 140861683
Canonical SMILES
COc1cccc2c(C[C@H](NC(=O)Cc3ccccc3)B(O)O)coc12
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Compound Formula C19H20BNO5
Compound Structure
Protein Name
Proteasome subunit beta type-8
Protein Classification
Enzyme
>
Protease
>
Threonine protease
>
Threonine protease PBT clan
>
Threonine protease T1A subfamily
Uniprot ID
P28062
Gene Name
PSMB8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1 Homo sapiens (Human)  1
1
IC50 = 8.9 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.2 nM