Brief Information of the Compound and Protein
Compound Name
[4-(3,4-dichloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl] (1S,4S)-5-prop-2-enoyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
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PubChem ID
CID: 168283079
Canonical SMILES
COc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3F)c2cc1OC(=O)N1C[C@@H]2C[C@H]1CN2C(=O)C=C
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Compound Formula C24H20Cl2FN5O4
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 0.3 nM
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   LI
   LO
   TS