Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[4-(3,4-dichloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl] (2R)-2-methyl-4-[2-(trifluoromethyl)prop-2-enoyl]piperazine-1-carboxylate
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 PubChem ID
CID: 168277427
Canonical SMILES
COc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3F)c2cc1OC(=O)N1CCN(C[C@H]1C)C(=O)C(=C)C(F)(F)F
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Compound Formula C25H21Cl2F4N5O4
Compound Structure
Protein Name
 Protein Info 
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 0.38 nM
   TI
   LI
   LO
   TS