Brief Information of the Compound and Protein
Compound Name
3-[2-[(N-ethyl-4-fluoroanilino)methyl]-7-fluoro-4-oxopyrazolo[1,5-a]pyrazin-5-yl]propanenitrile
    Show/Hide
PubChem ID
CID: 168292968
Canonical SMILES
CCN(Cc1cc2n(n1)c(F)cn(CCC#N)c2=O)c1ccc(F)cc1
    Show/Hide
Compound Formula C18H17F2N5O
Compound Structure
Protein Name
Glutamate receptor 2
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
Ionotropic glutamate receptor
>
AMPA receptor
Uniprot ID
P42262
Gene Name
GRIA2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 2800 nM
   TI
   LI
   LO
   TS