Brief Information of the Compound and Protein
Compound Name
6-amino-5-(3-hydroxy-2,6-dimethylphenyl)-2-(2-hydroxypropan-2-yl)pyrrolo[2,3-b]pyrazine-7-carboxamide
    Show/Hide
Canonical SMILES
Cc1ccc(O)c(C)c1-n1c(N)c(C(N)=O)c2nc(cnc12)C(C)(C)O
    Show/Hide
Compound Formula C18H21N5O3
Compound Structure
Protein Name
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
>
Other protein kinase WEE family
Uniprot ID
Q99640
Gene Name
PKMYT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000449 FU-OV-1 Homo sapiens (Human)  1
1
IC50 = 26 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 23 nM
   TI
   LI
   LO
   TS