Brief Information of the Compound and Protein
Compound Name
(2R)-2-(5-chloro-2-methoxypyridin-4-yl)-1-[(2S)-7-methyl-6-([1,2,4]triazolo[1,5-a]pyridin-2-yl)spiro[3,4-dihydro-1H-1,8-naphthyridine-2,3'-pyrrolidine]-1'-yl]propan-1-one
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Canonical SMILES
COc1cc([C@@H](C)C(=O)N2CC[C@]3(C2)CCc2cc(-c4nc5ccccn5n4)c(C)nc2N3)c(Cl)cn1
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Compound Formula C27H28ClN7O2
Compound Structure
Protein Name
Melanocortin receptor 4
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Melanocortin receptor
Uniprot ID
P32245
Gene Name
MC4R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 0.28 nM
   TI
   LI
   LO
   TS