Brief Information of the Compound and Protein
Compound Name
(2R)-2-(6-methoxy-2-methylpyrimidin-4-yl)-1-[(2S)-7-methyl-6-(2-methyltetrazol-5-yl)spiro[3,4-dihydro-1H-1,8-naphthyridine-2,3'-pyrrolidine]-1'-yl]propan-1-one
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Canonical SMILES
COc1cc(nc(C)n1)[C@@H](C)C(=O)N1CC[C@]2(C1)CCc1cc(-c3nnn(C)n3)c(C)nc1N2
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Compound Formula C23H29N9O2
Compound Structure
Protein Name
Melanocortin receptor 4
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Melanocortin receptor
Uniprot ID
P32245
Gene Name
MC4R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 0.54 nM
   TI
   LI
   LO
   TS