Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S)-2-[6-(difluoromethoxy)pyridin-3-yl]-1-[(2S)-7-methyl-6-pyrimidin-2-ylspiro[3,4-dihydro-1H-1,8-naphthyridine-2,3'-pyrrolidine]-1'-yl]propan-1-one
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 PubChem ID
CID: 166585467
Canonical SMILES
C[C@H](C(=O)N1CC[C@]2(C1)CCc1cc(c(C)nc1N2)-c1ncccn1)c1ccc(OC(F)F)nc1
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Compound Formula C25H26F2N6O2
Compound Structure
Protein Name
 Protein Info 
Melanocortin receptor 4
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Melanocortin receptor
Uniprot ID
P32245
Gene Name
MC4R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 0.44 nM
   TI
   LI
   LO
   TS