Brief Information of the Compound and Protein
Compound Name
1-[6-[6-amino-4-(trifluoromethyl)pyridin-3-yl]-2-morpholin-4-ylpyrimidin-4-yl]-3-phenylimidazolidin-2-one
    Show/Hide
PubChem ID
CID: 59507806
Canonical SMILES
Nc1cc(c(cn1)-c1cc(nc(n1)N1CCOCC1)N1CCN(C1=O)c1ccccc1)C(F)(F)F
    Show/Hide
Compound Formula C23H22F3N7O2
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
A0A0G2K344
Gene Name
PIK3CA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000019 Rat1 Rattus norvegicus (Rat)  1
1
IC50 = 606 nM
   TI
   LI
   LO
   TS