Brief Information of the Compound and Protein
Compound Name
(3aS,6aS)-3-[4-[2-amino-4-(trifluoromethyl)pyrimidin-5-yl]-6-morpholin-4-ylpyrimidin-2-yl]-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]oxazol-2-one
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PubChem ID
CID: 168271624
Canonical SMILES
Nc1ncc(-c2cc(nc(n2)N2[C@H]3COC[C@H]3OC2=O)N2CCOCC2)c(n1)C(F)(F)F
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Compound Formula C18H18F3N7O4
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
A0A0G2K344
Gene Name
PIK3CA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000019 Rat1 Rattus norvegicus (Rat)  1
1
IC50 = 214 nM
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