Brief Information of the Compound and Protein
Compound Name
(5R)-3-[4-[2-amino-4-(trifluoromethyl)pyrimidin-5-yl]-6-morpholin-4-ylpyrimidin-2-yl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one
    Show/Hide
PubChem ID
CID: 168276406
Canonical SMILES
Nc1ncc(-c2cc(nc(n2)N2C[C@H](CO)OC2=O)N2CCOCC2)c(n1)C(F)(F)F
    Show/Hide
Compound Formula C17H18F3N7O4
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
A0A0G2K344
Gene Name
PIK3CA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000019 Rat1 Rattus norvegicus (Rat)  1
1
IC50 = 158 nM
   TI
   LI
   LO
   TS