Brief Information of the Compound and Protein
Compound Name
1-[6-[6-amino-4-(trifluoromethyl)pyridin-3-yl]-2-morpholin-4-ylpyrimidin-4-yl]-1-(2-hydroxyethyl)-3-methylurea
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PubChem ID
CID: 168270146
Canonical SMILES
CNC(=O)N(CCO)c1cc(nc(n1)N1CCOCC1)-c1cnc(N)cc1C(F)(F)F
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Compound Formula C18H22F3N7O3
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
A0A0G2K344
Gene Name
PIK3CA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000019 Rat1 Rattus norvegicus (Rat)  1
1
IC50 = 3060 nM
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   LI
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   TS