Brief Information of the Compound and Protein
Compound Name
US9284315, BEZ-235
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PubChem ID
CID: 11977753
SID: 26746658
Canonical SMILES
Cn1c2cnc3ccc(cc3c2n(-c2ccc(cc2)C(C)(C)C#N)c1=O)-c1cnc2ccccc2c1
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Compound Formula C30H23N5O
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
A0A0G2K344
Gene Name
PIK3CA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000019 Rat1 Rattus norvegicus (Rat)  1
1
IC50 = 5.3 nM
   TI
   LI
   LO
   TS