Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[6-chloro-4-(3-ethenyl-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl)-8-fluoro-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]quinazolin-7-yl]naphthalen-2-ol
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 PubChem ID
CID: 163680219
Canonical SMILES
CN1CCC[C@H]1COc1nc(N2CCn3c(C2)cnc3C=C)c2cc(Cl)c(c(F)c2n1)-c1cc(O)cc2ccccc12
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Compound Formula C32H30ClFN6O2
Compound Structure
Protein Name
 Protein Info 
GTPase KRas
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
P01116
Gene Name
KRAS
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000207 MIA PaCa-2
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 100 nM