Brief Information of the Compound and Protein
Compound Name
Bms-986165
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PubChem ID
CID: 134821691
Canonical SMILES
[2H]C([2H])([2H])NC(=O)c1nnc(NC(=O)C2CC2)cc1Nc1cccc(-c2ncn(C)n2)c1OC
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Compound Formula C20H22N8O3
Compound Structure
Protein Name
Non-receptor tyrosine-protein kinase TYK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
P29597
Gene Name
TYK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
IC50 = 3.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.2 nM
2 IC50 > 10000 nM
3 Ki = 0.02 nM