Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(3,5-Dimethyl-[1,2,4]triazol-1-yl)-1-[(R)-2-methyl-4-(4-(5-trifluoromethoxy-1H-benzoimidazol-2-yl)-2-trifluoromethyl-thiazol-5-yl]-piperazin-1-yl]-ethanone
    Show/Hide
 PubChem ID
CID: 168282969
Canonical SMILES
C[C@@H]1CN(c2sc(C(F)(F)F)nc2-c2nc3ccc(OC(F)(F)F)cc3[nH]2)CCN1C(=O)Cn1cnc2cccnc21
    Show/Hide
Compound Formula C25H20F6N8O2S
Compound Structure
Protein Name
 Protein Info 
C-X-C chemokine receptor type 3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CXC chemokine receptor
Uniprot ID
P49682
Gene Name
CXCR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 3.6 nM
   TI
   LI
   LO
   TS