Brief Information of the Compound and Protein
Compound Name
 Compound Info 
methyl 6-[[5-chloro-4-[2-(methylcarbamoyl)anilino]pyrimidin-2-yl]amino]-2-methyl-1H-indole-3-carboxylate
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 PubChem ID
CID: 159899797
Canonical SMILES
CNC(=O)c1ccccc1Nc1nc(Nc2ccc3c(C(=O)OC)c(C)[nH]c3c2)ncc1Cl
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Compound Formula C23H21ClN6O3
Compound Structure
Protein Name
 Protein Info 
ALK tyrosine kinase receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
Q9UM73
Gene Name
ALK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  3
1
IC50 = 3 nM
   TI
   LI
   LO
   TS
2
IC50 = 3.4 nM
   TI
   LI
   LO
   TS
3
IC50 = 6.3 nM
   TI
   LI
   LO
   TS