Brief Information of the Compound and Protein
Compound Name
3-(1H-indazol-3-yl)-5-(prop-2-enoylamino)-N-prop-2-ynylbenzamide
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PubChem ID
CID: 154700546
Canonical SMILES
C=CC(=O)Nc1cc(cc(c1)-c1n[nH]c2ccccc12)C(=O)NCC#C
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Compound Formula C20H16N4O2
Compound Structure
Protein Name
Dual specificity mitogen-activated protein kinase kinase 7
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase STE7 family
Uniprot ID
O14733
Gene Name
MAP2K7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
EC50 < 100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 6.5 nM