Brief Information of the Compound and Protein
Compound Name
5-[2-(2,6-difluoro-3,5-dimethoxyphenyl)ethyl]-N-[3-methoxy-4-(4-methylpiperazin-1-yl)phenyl]pyrimidin-2-amine
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PubChem ID
CID: 71736247
Canonical SMILES
COc1cc(OC)c(F)c(CCc2cnc(Nc3ccc(N4CCN(C)CC4)c(OC)c3)nc2)c1F
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Compound Formula C26H31F2N5O3
Compound Structure
Protein Name
Fibroblast growth factor receptor 3
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase FGFR family
Uniprot ID
P22607
Gene Name
FGFR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 1.5 nM
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