Brief Information of the Compound and Protein
Compound Name
5-[(2,6-difluoro-3,5-dimethoxyphenyl)methoxy]-N-[1-(2-piperazin-1-ylethyl)pyrazol-4-yl]pyrimidin-2-amine;trihydrochloride
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PubChem ID
CID: 168291722
Canonical SMILES
Cl.Cl.Cl.COc1cc(OC)c(F)c(COc2cnc(Nc3cnn(CCN4CCNCC4)c3)nc2)c1F
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Compound Formula C22H30Cl3F2N7O3
Compound Structure
Protein Name
Fibroblast growth factor receptor 3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P22607
Gene Name
FGFR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 1.2 nM
   TI
   LI
   LO
   TS