Brief Information of the Compound and Protein
Compound Name
5-[(2,6-difluoro-3,5-dimethoxyphenyl)methoxy]-N-[3-fluoro-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidin-2-amine
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PubChem ID
CID: 129180276
Canonical SMILES
COc1cc(OC)c(F)c(COc2cnc(Nc3ccc(N4CCC(CC4)N4CCN(C)CC4)c(F)c3)nc2)c1F
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Compound Formula C29H35F3N6O3
Compound Structure
Protein Name
Fibroblast growth factor receptor 3
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
>
TK protein kinase group
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Tyrosine protein kinase FGFR family
Uniprot ID
P22607
Gene Name
FGFR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 < 1 nM
   TI
   LI
   LO
   TS