Brief Information of the Compound and Protein
Compound Name
N-[5-[(2,6-difluoro-3,5-dimethoxyphenyl)methoxy]pyrimidin-2-yl]-2-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]pyrimidin-5-amine
    Show/Hide
PubChem ID
CID: 90166111
Canonical SMILES
COc1cc(OC)c(F)c(COc2cnc(Nc3cnc(nc3)N3CCC(CC3)N3CCN(C)CC3)nc2)c1F
    Show/Hide
Compound Formula C27H34F2N8O3
Compound Structure
Protein Name
Fibroblast growth factor receptor 3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P22607
Gene Name
FGFR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 4.5 nM
   TI
   LI
   LO
   TS