Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[2-(2,6-difluoro-3,5-dimethoxyphenyl)ethyl]-N-[3-methoxy-4-[4-[methyl-(1-methylpiperidin-4-yl)amino]piperidin-1-yl]phenyl]pyrimidin-2-amine;tetrahydrochloride
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 PubChem ID
CID: 168280474
Canonical SMILES
Cl.Cl.Cl.Cl.COc1cc(OC)c(F)c(CCc2cnc(Nc3ccc(N4CCC(CC4)N(C)C4CCN(C)CC4)c(OC)c3)nc2)c1F
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Compound Formula C33H48Cl4F2N6O3
Compound Structure
Protein Name
 Protein Info 
Fibroblast growth factor receptor 3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P22607
Gene Name
FGFR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 1.1 nM
   TI
   LI
   LO
   TS