Brief Information of the Compound and Protein
Compound Name
ASP-5878
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PubChem ID
CID: 71736582
Canonical SMILES
COc1cc(OC)c(F)c(COc2cnc(Nc3cnn(CCO)c3)nc2)c1F
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Compound Formula C18H19F2N5O4
Compound Structure
Protein Name
Fibroblast growth factor receptor 3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P22607
Gene Name
FGFR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 2.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.47 nM
2 IC50 = 3.5 nM