Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-1-yl)-2-[5-[2-[4-[(4-hydroxypiperidin-1-yl)methyl]phenyl]ethynyl]-3-oxo-1H-isoindol-2-yl]-N-(1,3-thiazol-2-yl)acetamide
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 PubChem ID
CID: 168278656
Canonical SMILES
OC1CCN(Cc2ccc(cc2)C#Cc2ccc3CN(C(C(=O)Nc4nccs4)c4ncn5CCCc45)C(=O)c3c2)CC1
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Compound Formula C33H32N6O3S
Compound Structure
Protein Name
 Protein Info 
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  2
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
2
IC50 = 297 nM
   TI
   LI
   LO
   TS