Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[4,7-dichloro-6-[4-(4-ethylpiperazin-1-yl)phenyl]indazol-2-yl]-2-[(6R)-6-fluoro-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-1-yl]-N-(1,3-thiazol-2-yl)acetamide
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 PubChem ID
CID: 155412952
Canonical SMILES
CCN1CCN(CC1)c1ccc(cc1)-c1cc(Cl)c2cn(nc2c1Cl)C(C(=O)Nc1nccs1)c1ncn2C[C@H](F)Cc12
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Compound Formula C30H29Cl2FN8OS
Compound Structure
Protein Name
 Protein Info 
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  2
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
2
IC50 = 15 nM
   TI
   LI
   LO
   TS