Brief Information of the Compound and Protein
Compound Name
4,5-dibromo-3-methyl-1-(piperazin-1-yl)-7,8-dihydro-6H-imidazo[4,5,1-ij]quinoline hydrochloride
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PubChem ID
CID: 73776232
Canonical SMILES
Cc1c(Br)c(Br)c2c3c1nc(N1CCNCC1)n3CCC2.Cl
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Compound Formula C15H19Br2ClN4
Compound Structure
Protein Name
Cyclin-dependent kinase 8
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase CDK family
>
CMGC protein kinase CDK8 subfamily
Uniprot ID
P49336
Gene Name
CDK8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000067 HCT 116 Homo sapiens (Human)  1
1
IC50 = 7400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.4 nM
2 IC50 = 37.2 nM