Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(3,5-difluorophenyl)-3-[3-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]propanamide
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 PubChem ID
CID: 168279268
Canonical SMILES
Fc1cc(F)cc(NC(=O)CCc2cccc(c2)-c2cnc3[nH]ccc3c2)c1
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Compound Formula C22H17F2N3O
Compound Structure
Protein Name
 Protein Info 
Cyclin-dependent kinase 8
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase CDK family
>
CMGC protein kinase CDK8 subfamily
Uniprot ID
P49336
Gene Name
CDK8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000067 HCT 116
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 3100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 62.8 nM