Brief Information of the Compound and Protein
Compound Name
N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[3-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]propanamide
    Show/Hide
PubChem ID
CID: 168280458
Canonical SMILES
CN1CCN(Cc2ccc(NC(=O)CCc3cccc(c3)-c3cnc4[nH]ccc4c3)cc2C(F)(F)F)CC1
    Show/Hide
Compound Formula C29H30F3N5O
Compound Structure
Protein Name
Cyclin-dependent kinase 8
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase CDK family
>
CMGC protein kinase CDK8 subfamily
Uniprot ID
P49336
Gene Name
CDK8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000067 HCT 116 Homo sapiens (Human)  1
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS