Brief Information of the Compound and Protein
Compound Name
(1R,3S)-1-(4-fluorophenyl)-N-[(4-fluorophenyl)methyl]-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
    Show/Hide
PubChem ID
CID: 168285367
Canonical SMILES
Oc1cc2C[C@H](N[C@H](c3ccc(F)cc3)c2cc1O)C(=O)NCc1ccc(F)cc1
    Show/Hide
Compound Formula C23H20F2N2O3
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily M member 8
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Transient receptor potential channel
Uniprot ID
Q8R455
Gene Name
TRPM8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 850 nM
   TI
   LI
   LO
   TS