Brief Information of the Compound and Protein
Compound Name
(5R,10aS)-5-(4-fluorophenyl)-7,8-dihydroxy-2-[3-(trifluoromethyl)phenyl]-10,10a-dihydro-5H-imidazo[1,5-b]isoquinoline-1,3-dione
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PubChem ID
CID: 168293324
Canonical SMILES
Oc1cc2C[C@@H]3N([C@H](c4ccc(F)cc4)c2cc1O)C(=O)N(C3=O)c1cccc(c1)C(F)(F)F
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Compound Formula C24H16F4N2O4
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily M member 8
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
Q8R455
Gene Name
TRPM8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 1200 nM
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   LI
   LO
   TS