Brief Information of the Compound and Protein
Compound Name
 Compound Info 
PF-477736
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 PubChem ID
CID: 135565545
SID: 26738683
Canonical SMILES
Cn1cc(-c2[nH]c3cc(NC(=O)[C@H](N)C4CCCCC4)cc4c3c2C=NNC4=O)cn1
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Compound Formula C22H25N7O2
Compound Structure
Protein Name
 Protein Info 
LIM domain kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase LISK family
>
TKL protein kinase LIMK subfamily
Uniprot ID
P53671
Gene Name
LIMK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 275.42 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3388.44 nM
2 IC50 > 10000 nM