Brief Information of the Compound and Protein
Compound Name
1-(2-hydroxyethyl)-3-[4-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl]-1-phenylurea
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PubChem ID
CID: 45381385
SID: 93373052
Canonical SMILES
Cc1c[nH]c2ncnc(-c3ccc(NC(=O)N(CCO)c4ccccc4)cc3)c12
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Compound Formula C22H21N5O2
Compound Structure
Protein Name
LIM domain kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase LISK family
>
TKL protein kinase LIMK subfamily
Uniprot ID
P53671
Gene Name
LIMK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 549.54 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 24 nM
2 IC50 = 1905.46 nM
3 IC50 > 10000 nM