Brief Information of the Compound and Protein
Compound Name
 Compound Info 
BMS-354825
    Show/Hide
 PubChem ID
CID: 3062316
SID: 12015788
Canonical SMILES
Cc1nc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)cc(n1)N1CCN(CCO)CC1
    Show/Hide
Compound Formula C22H26ClN7O2S
Compound Structure
Protein Name
 Protein Info 
LIM domain kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase LISK family
>
TKL protein kinase LIMK subfamily
Uniprot ID
P53671
Gene Name
LIMK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 263.03 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 223.87 nM
2 IC50 = 1513.56 nM
3 Kd = 86 nM