Brief Information of the Compound and Protein
Compound Name
N-[12-[4-[4-[[8-(3-acetamidophenyl)-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl]amino]-3-methoxyphenyl]piperazin-1-yl]dodecyl]-2-(1-adamantyl)acetamide
    Show/Hide
PubChem ID
CID: 168271926
Canonical SMILES
COc1cc(ccc1Nc1ncc2c(C)cc(=O)n(-c3cccc(NC(C)=O)c3)c2n1)N1CCN(CCCCCCCCCCCCNC(=O)CC23CC4CC(CC(C4)C2)C3)CC1
    Show/Hide
Compound Formula C51H70N8O4
Compound Structure
Protein Name
RAC-gamma serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase AKT family
Uniprot ID
Q9Y243
Gene Name
AKT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000157 NCI-H1975 Homo sapiens (Human)  1
1
EC50 = 67 nM
   TI
   LI
   LO
   TS