Brief Information of the Compound and Protein
Compound Name
(1R,3R)-3-[(3-bromo-1-quinolin-6-ylpyrazolo[3,4-d]pyrimidin-6-yl)amino]-N-methylcyclopentane-1-carboxamide
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PubChem ID
CID: 151341389
Canonical SMILES
CNC(=O)[C@@H]1CC[C@H](C1)Nc1ncc2c(Br)nn(-c3ccc4ncccc4c3)c2n1
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Compound Formula C21H20BrN7O
Compound Structure
Protein Name
eIF-2-alpha kinase GCN2
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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Other protein kinase group
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Other protein kinase PEK family
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Other protein kinase GCN2 subfamily
Uniprot ID
Q9P2K8
Gene Name
EIF2AK4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000084 SK-OV-3 Homo sapiens (Human)  1
1
IC50 = 25 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 21 nM