Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US11479551, Example 16-7
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 PubChem ID
CID: 156151242
Canonical SMILES
Cn1ncc(c1-c1c(F)c(Cl)cc(OC2CC2)c1C#N)-c1ccc2c(c1)c(CN)n[nH]c2=O
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Compound Formula C23H18ClFN6O2
Compound Structure
Protein Name
 Protein Info 
Protein arginine N-methyltransferase 5
Protein Classification
Epigenetic regulator
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Writer
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Protein methyltransferase
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Protein arginine methyltransferase
Uniprot ID
O14744
Gene Name
PRMT5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000067 HCT 116
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 8 nM
   TI
   LI
   LO
   TS
2
IC50 = 653 nM
   TI
   LI
   LO
   TS