Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
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 PubChem ID
CID: 60961
SID: 81044335
Canonical SMILES
Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
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Compound Formula C10H13N5O4
Compound Structure
Protein Name
 Protein Info 
Adenosine receptor A1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Nucleotide-like receptor (family A GPCR)
>
Adenosine receptor
Uniprot ID
P30542
Gene Name
ADORA1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 310 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 69.18 nM
   TI
   LI
   LO
   TS
2
IC50 = 2.344 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
Kd = 295.12 nM
   TI
   LI
   LO
   TS
2
Ki = 812.83 nM
   TI
   LI
   LO
   TS
CL000314 HEK293T/17
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 39 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 310 nM