Brief Information of the Compound and Protein
Compound Name
N-[3-[(3R,6R)-5-amino-3,6-dimethyl-6-(trifluoromethyl)-2H-1,4-oxazin-3-yl]-4-fluorophenyl]-3-chloro-5-cyanopyridine-2-carboxamide
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PubChem ID
CID: 86699708
Canonical SMILES
C[C@]1(CO[C@](C)(C(N)=N1)C(F)(F)F)c1cc(NC(=O)c2ncc(cc2Cl)C#N)ccc1F
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Compound Formula C20H16ClF4N5O2
Compound Structure
Protein Name
Amyloid-beta precursor protein
Protein Classification
Membrane receptor
Uniprot ID
P05067
Gene Name
APP
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 4 nM
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