Brief Information of the Compound and Protein
Compound Name
3-amino-N-[6-[(3R,6R)-5-amino-3,6-dimethyl-6-(trifluoromethyl)-2H-1,4-oxazin-3-yl]-5-fluoropyridin-2-yl]-5-(2-fluoroethoxy)pyrazine-2-carboxamide
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PubChem ID
CID: 166636413
Canonical SMILES
C[C@]1(CO[C@](C)(C(N)=N1)C(F)(F)F)c1nc(NC(=O)c2ncc(OCCF)nc2N)ccc1F
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Compound Formula C19H20F5N7O3
Compound Structure
Protein Name
Amyloid-beta precursor protein
Protein Classification
Membrane receptor
Uniprot ID
P05067
Gene Name
APP
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 263 nM
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