Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[[4-chloro-2-(trifluoromethyl)phenyl]methyl]-N-[(4-ethylsulfonylphenyl)methyl]-1-(2-fluoroethyl)indole-5-carboxamide
    Show/Hide
 PubChem ID
CID: 130432898
Canonical SMILES
CCS(=O)(=O)c1ccc(CNC(=O)c2ccc3n(CCF)c(Cc4ccc(Cl)cc4C(F)(F)F)cc3c2)cc1
    Show/Hide
Compound Formula C28H25ClF4N2O3S
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group F
>
Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 2 nM