Brief Information of the Compound and Protein
Compound Name
 Compound Info 
14C-5-hydroxy tryptamine creatinine disulfate
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 PubChem ID
CID: 5202
SID: 15120541
Canonical SMILES
NCCc1c[nH]c2ccc(O)cc12
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Compound Formula C10H12N2O
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 2B
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P41595
Gene Name
HTR2B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
EC50 = 1.5 nM
   TI
   LI
   LO
   TS
2
EC50 = 4.5 nM
   TI
   LI
   LO
   TS
3
Ki = 13 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 4.5 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  5
1
EC50 = 0.5 nM
   TI
   LI
   LO
   TS
2
EC50 = 0.86 nM
   TI
   LI
   LO
   TS
3
EC50 = 0.92 nM
   TI
   LI
   LO
   TS
4
EC50 = 25.12 nM
   TI
   LI
   LO
   TS
5
Ki = 10.8 nM
   TI
   LI
   LO
   TS
CL000065 HEK293-EBNA
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 5.8 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 12 nM
2 Ki = 13 nM
3 Ki = 13.49 nM